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doi: 10.1055/s-2007-1024754

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Its binding constant (pKa 16.44) is similar to albumin's copper transport site (log = 16.2), allowing GHK to exchange copper with albumin for intracellular delivery.[3] Discovery and design rationale GHK was first identified in 1973 in fractions of human plasma that promoted survival of liver cells in culture

The upregulated genes handle tissue repair, collagen synthesis, and antioxidant defense