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GLP-1 receptor agonists have therefore emerged as a promising adjunct in the HS treatment landscape, given their established metabolic benefits and emerging evidence suggesting anti-inflammatory effects

However, the longer-term impact of GLP-1RAs is likely to be positive for the industry, driven by an expected higher uptake of physical activity by previously overweight individuals, and the growing evidence of the importance of exercise to preserving muscle mass

Cause-specific mortality (cardiovascular versus non-cardiovascular) was not independently adjudicated due to limitations in structured documentation within the electronic medical record system