Most of the product licences, or marketing authorities as they are called in the UK, for hydroxocobalamin date from the 1990s when the requirement for evidence was different than it is now
Song HA, Jang SY, Park MJ, Kim SW, Kang CG, Lee JH, Kim HJ, Kim J, Lee JK, Chung KS, Lee KT (2024) Immunostimulation signaling via toll-like receptor 2 activation: a molecular mechanism of Lactococcus lactis OTG1204 in vitro and in vivo
J Alzheimers Dis 2015;44:705-20
When used topically, studies have shown that glutathione lightens and brightens the skin by inhibiting melanin while fighting dark spots & hyperpigmentation
Prior to counterstaining and mounting, the slides were incubated with the primary antibodies at 4C overnight and then rinsed with phosphate-buffered saline (PBS) three times for five min each
Much of the published literature involves in vitro and animal models investigating mucosal protection, angiogenesis, and musculoskeletal repair biology