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The goal is consistent, sustainable activity, not exhaustive workouts that trigger flare responses

Factors influencing response include baseline metabolic health, dietary adherence during treatment, physical activity levels, genetic factors affecting drug metabolism, and starting weight

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79 NovinscakT.BrcicL.StaresinicM.JukicI.RadicB.PevecD.et al (2008)

In UK clinical practice, co-prescribing these medications is generally not recommended due to overlapping pathways and limited additional benefit

Body fat distribution, fasting insulin levels, and insulin secretion: A bidirectional mendelian randomization study