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This section summarizes various compounds that can suppress ferroptosis and their roles in the metabolic and molecular pathways associated with ferroptosis
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They developed a new kind of DAC by conjugating a PROTAC that degrades BRD4 with an ROR1 antibody (Fig
This reduces the production of pro-swelling cytokines (TNF-, IL-1, IL-6), swelling enzymes (COX-2, iNOS), and other swelling mediators that can cause tissue damage when produced in excess
In contrast, a brain-directed trophic product may be better suited to chronic disability when the goal is to enhance plasticity and function
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