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(Accessed on 14 April 2025) United States Renal Data System (2023) 2023 Annual data report

That opens the door to future research: If scientists can find ways to safely boost GLP-1 output from alpha cells they may be able to naturally enhance insulin secretion in people with diabetes

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If the monthly arm comes in materially lower, prescribers will treat monthly as a convenience option for a subset, not the default

In select cases particularly patients with: Obesity High insulin resistance Very high total daily insulin requirements endocrinologists may consider off-label use with: Continuous glucose monitoring Routine ketone monitoring Strict sick-day protocols Close specialist follow-up But this is not standard therapy