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Phase 4: maintenance (week 19 onward) Maintenance is not a single dose

Gut 1991, 32: 766-773

Does Split Dosing Reduce GI Side Effects

Gedalia built TrufaMED around physician-led protocols, Joint Commission accreditation, and a standard of care usually reserved for hospital systems

10.1038/s41586-019-1705-2 8 Bosello-TravainV.ConradM.CozzaG.NegroA.QuartesanS.RossettoM.et al (2013)

It helps researchers explore how coordinated receptor activation influences glucose metabolism, lipid regulation, energy expenditure, and hormonal communication in cellular and animal models