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Compared to older compounds in the same class, it shows little effect on cortisol, prolactin, and ACTH
Tirzepatide is a novel glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for the treatment of type 2 diabetes mellitus under the brand name Mounjaro, and for chronic weight management as Zepbound
According to market data, allowed PMPM costs for employers covering GLP-1s for weight management rose from $2.41 in 2022 to $22.59 in 2024
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The identification of the UGTs that mediate the conjugation of active bupropion metabolites is crucial for understanding factors that could affect potential DDIs
The metabolic adaptation that follows discontinuation is profound
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