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doi:10.1016/j.mce.2008.08.012 Myat A, Redwood SR, Gersh BJ, Yellon DM, Marber MS

In the Phase 2 trial protocol, participants reached the 12mg maximum dose at week 20 after five escalation steps (1mg, 2mg, 4mg, 8mg, 12mg), each held for four weeks

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The trial also found that oral semaglutide results in faster weight loss than placebo, with the average time to achieve at least 5% weight loss being 12 weeks, compared to 40 weeks with placebo

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