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Transfected and parental FlpInCHO cells were maintained in DMEM supplemented with 10% heat-inactivated FBS and incubated in a humidified environment at 37 C in 5% CO 2

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The therapy is indicated for use in combination with a reduced-calorie diet and increased physical activity

Long chain acetylcarnitine esters transport fatty acyl moieties into the mitochondria (Figure 2)