This leads to increased endurance, better metabolic efficiency, and reduced fatigue, helping counteract age-related declines in energy
Hepatitis C virus induces oxidative stress, DNA damage and modulates the DNA repair enzyme NEIL1
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Available from: Chu GX, Ling Q, Guo ZG
This process, along with GCL inhibition and the formation of mixed disulfides between GSH and protein sulfhydryl, concurred to a steady-state decrement of free GSH concentration and, consequently, to an intracellular redox state shift toward more oxidizing conditions, which could be required for avoiding fast reduction of oxidized cysteines allowing the upstream ROS-induced autophagic stimulus to be propagated