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(3) comparison (control): assessing a group of patients as control group not receiving GLP-1 agonists (including placebo, other medications, lifestyle or diet intervention)
GLP-1 stands for glucagon-like peptide-1 , a hormone made in the intestines
While GLP-1 drugs are remarkably effective, they often also cause side effects like gastrointestinal distress and muscle loss
Sikorska et al., 2008), we raise the following questions: (i) does the observed methylation of Sox2 in astrocytes also occur in aged stem cells and would it decrease their ability to differentiate and give rise to new neurons
Attias more recent take is that the loss is not beyond what the weight loss would predict, and that strength and physical function usually improve, not decline
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