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Based on class data from authorised GLP-1 RA SmPCs, prescribers should consider therapeutic drug monitoring or clinical assessment when initiating retatrutide in patients taking medicines such as: Digoxin used for heart failure and atrial fibrillation
More relevant to the GLP-1 claims, a separate 8-week randomized controlled crossover trial published in the European Journal of Nutrition found that participants taking the polyphenolic extract experienced a 12% increase in GLP-1 after breakfast and a 22% increase after lunch compared to placebo
doi: 10.1038/s41421-024-00750-4 181 ZhuJWangHLiuYLiWCaoLWangWet al
Doubling doses is not recommended
Preliminary data suggests that retatrutide could lead to more weight loss than semaglutide or tirzepatide because it targets more receptors involved in suppressing appetite and lowering blood sugar
To administer Zepbound using the Zepbound pen, follow these steps: Prepare the Pen : Inspect the pen for any damage and check the expiration date
