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That rate was no higher than in the comparison groups: women with diabetes taking other medications, and women with obesity not taking a GLP-1
Both agents affect insulin sensitivity and glucose regulation, creating unpredictable risks including glucose dysregulation when used together
Metformin typically causes gastrointestinal symptoms like nausea or loose stools, while semaglutide may produce mild nausea during dose escalation
The April 2024 Phase 3 readout in type 2 diabetes reported a 14.2% mean body-weight reduction at 68 weeks for CagriSema 2.4mg/2.4mg versus 10.2% for semaglutide 2.4mg alone [4]
These C-cells produce a hormone called calcitonin, which helps regulate calcium levels in your blood
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