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doi: 10.1016/j.eprac.2025.07.017

According to the FDA's official guidance (updated April 2026 at fda.gov), the semaglutide injection shortage was resolved on February 21, 2025, and the transitional exemption windows for compounders operating under the shortage exemption subsequently ended - for 503A pharmacies by April 22, 2025, and for 503B outsourcing facilities by May 22, 2025

Safety Considerations When Using Allulose Allulose is generally recognised as well-tolerated when consumed in moderate amounts, though several safety considerations warrant attention

Frequency: Once per week maximum for at-home treatment