L-Glutathione (GSH) is a thiol-containing tripeptide that acts directly as an antioxidant, neutralizing reactive oxygen species, free radicals, peroxides, and lipid peroxides
Aged garlic extract have also been shown to increase expression of antioxidant enzymes via the Nrf2/ARE pathway (24)
10.3389/fncel.2018.00288 63 ShiW.WeiX.WangZ.HanH.FuY.LiuJ.et al
Among the most popular options are N-acetylcysteine (NAC) and glutathione
Overall, these findings demonstrate that this substrate profiling system can both predict and validate physiologically relevant off-target cleavage events, thereby providing critical information for refining protease specificity for intended applications
The real-world disparities compared with clinical trials underscore the need for broader studies to better predict response and guide individualised treatment strategies in type 2 diabetes