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Patient-dependent conditions affecting the effectiveness of treatment or, quite possibly, affecting outcomes through the gut microbiota, however, are still to be established
Supports a strong, resilient skin barrier
In sepsis-induced AKI models, PKM2 inhibition attenuates the activation of NLR family pyrin domain containing 3 (NLRP3) and absent in melanoma 2 (AIM2) inflammasomes, decreases the release of IL-1, IL-18, and HMGB1 by macrophages, and ultimately improves survival outcomes (Xie et al., 2016)
Vandewoude, M., Claeys, M., Leeuw, I., 1984
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