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As for why people opted to microdose, avoiding side effects was the main reason for 66 percent of microdosers, while 38 percent said they did it to save money
Mounjaro is priced at around $980 while Wegovy costs about $1,350 and provides an improved side effect profile for patients
The phase 2 type 2 diabetes trial evaluated maintenance doses including 0.5 mg, 4 mg, 8 mg, and 12 mg, with several escalation designs [5]
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The rebound effect upon GLP-1R agonists withdrawal needs to be investigated further, and new drug developments should aim to mitigate this big limitation and find ways in which GLP-1R agonists could be used as short-term therapies without causing weight regain and cardiometabolic risk reversal
We strongly advise against stockpiling, as this can create supply pressures
