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Mu C, Corley MJ, Lee RWY, Wong M, Pang A, Arakaki G, et al
Hyperglycemia and the ensuing glucotoxicity exert their deleterious effects via myriad mechanisms, including ROS stress, ER stress, inflammation, and hypoxia 28
Furthermore, LC may positively influence the nutritional status of HD patients by promoting a positive protein balance, and by reducing insulin resistance and chronic inflammation, possibly through an effect on leptin resistance [54]
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The synergistic effect of activating all three receptors simultaneously promotes significant weight loss and better metabolic control than other existing GLP-1 receptor agonists, such as semaglutide (Wegovy and Ozempic), liraglutide, dulaglutide, and dual-agonists like tirzepatide (Mounjaro and Zepbound)
