Still, I expect as is generally the case, real-world effectiveness will be substantially lower than clinical efficacy
This conversation is particularly important for individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN 2), as these represent absolute contraindications to the use of products with the thyroid C-cell tumor boxed warning, including semaglutide, liraglutide, dulaglutide, exenatide extended-release, and tirzepatide
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Aim for 0.7-1 gram of protein per pound of body weight to preserve muscle mass during weight loss
Though be careful, as loss of muscle mass with GLP-1 is a real issue, thus instituting a concurrent resistance exercise program is important
Endocr Pract 2018