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Candidates may include those who: Struggle to lose weight despite consistent efforts diet and exercise efforts Experience strong hunger signals or persistent cravings Have metabolic conditions, such as insulin resistance or type 2 diabetes Are looking for medically supervised support for long-term weight management A health care clinician can help determine if GLP-1 medications are right for you based on your medical history and health goals
Dosage: 1-2 mcg/kg, 1-2 times daily via subcutaneous injection
No Prescription Required: A real GLP-1 medication requires a prescription from a licensed healthcare provider
BMJ Case Rep (2014) 2014
Semaglutide (sold as Ozempic) was approved to treat type 2 diabetes in December 2017 and for obesity (sold as Wegovy) in June 2021
The Cyp2e1 effect is specific to GLP-1 receptor activation and would therefore be expected to apply to retatrutide's GLP-1 component as well
