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doi: 10.2337/db17-1212 45 MosenzonO.BlicherT

Malignant brain tumors known as glioma or glioblastoma exploit this phenomenon by using glutamate as an energy source, especially when these tumors become more dependent on glutamate due to mutations in the gene IDH1

Tirzepatide is a dual incretin receptor agonist, meaning it activates both the glucagon-like peptide-1 (GLP-1) receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor

This regulated necrotic cell death is activated in response to Fas/FasL signaling, CD59 ligation combined with pore formation, mediated by ROS, ceramide, and advanced glycation end products (AGEs) [28]

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