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Seiwerth et al., Frontiers in Pharmacology (2021) and Xing et al., Int J Mol Sci (2021)
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Neither compound should be considered a licensed medicine in the UK, and both require careful scrutiny before any consideration of use
Extreme deficits (800-1,000 calories below maintenance) are unnecessary and counterproductive because they increase muscle catabolism and metabolic adaptation
Dermauw W, Wybouw N, Rombauts S, Menten B, Vontas J, Grbic M
Brain and Tissue Half-Life However, Dihexa's mechanism involves sustained changes in receptor signalling, gene expression, and synaptic plasticity
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