It's important to note that GLP-1 medications are not FDA-approved for treating cognitive impairment or brain fog, and should not be prescribed specifically for these indications
This allocation resulted in 18 participants receiving PG-102 and 6 receiving a placebo
Sources Retatrutide Phase 2 obesity trial PubMed summary of the NEJM trial (includes dosing groups and weightloss results) Mounjaro UK prescribing document (official SmPC) MHRA warning on unlicensed pens Phase 3 TRIUMPH programme
Shih and our team: Examine your medical background, current medications, and prior attempts at dieting or exercise strategies

"GLP-1 receptor agonists should be prescribed alongside structured lifestyle interventionsspecifically resistance training at least 3 times weekly, 150 minutes of moderate-intensity aerobic exercise weekly, and nutrient-dense dietary counselingto preserve muscle and bone mass, optimize weight loss, and improve cardiometabolic outcomes." "Protein intake alone is insufficient without structured resistance training, and combination therapy produces superior metabolic benefits compared to pharmacotherapy alone, including better preservation of lean mass, improved cardiorespiratory fitness, and prevention of GLP-1-associated increases in resting heart rate." I wrote earlier about this balance in a piece called The central idea still holds: GLP-1 medications can improve metabolic markers dramatically, but without strength training and adequate nutrition, people may lose meaningful lean mass
Add it to a smoothie, stir it into yogurt, or mix it with oats