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The Aib substitution introduces a gem-dimethyl group on the alpha-carbon, creating steric hindrance that prevents DPP-4 from accessing the scissile bond
In this sense, beneficial mutations are not random improvements in abstraction
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Fermented Oyster Extract Promotes Osteoblast Differentiation by Activating the Wnt/-Catenin Signaling Pathway, Leading to Bone Formation
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