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The increase in Akt and ERK phosphorylations lead to cardiomyocyte growth and activation of glucose metabolism [24],[39]-[41]
By addressing these physiological signals, the medications support sustainable weight management when combined with healthy lifestyle choices
10.1002/syn.21990 253 RondoC
Considering the above, future lines of research should focus on the proper dose, timing, safety and frequency when administering GLP-1 analogs and conjugated estradiol as a treatment for body weight disorders
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