Neuropsychiatric disturbances in SLE are associated with antibodies against NMDA receptors
Ethics declarations Ethics approval and consent to participate The information on prior prescription data involved in this study was obtained from our hospitals prescription audit management system, and the ADEs data information was obtained from the FAERS database
Initially, resting immune cells tend to polarize towards pro-inflammatory phenotypes, releasing pro-inflammatory and chemotactic factors to recruit assistance, often through MAPK, NF-B, and other signaling pathways
Psychological distress was assessed using the Kessler Psychological Distress Scale (K6), which measures non-specific psychological distress in the past month (possible range = 024) [35, 36]
Therefore, a PS-MP concentration of 30 mg/kg (designated as the PS-MP treatment group) was used for subsequent experiments to further investigate the reproductive toxicity of PS-MPs in female mice
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