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Central nervous system applications are an active growth area, with documented effects on dopamine and serotonin pathway markers, traumatic brain injury models, and spinal cord research preparations

Dosages in animal studies: In the vast majority of preclinical studies, the doses used in rats range between 10 g/kg and 10 ng/kg of body weight, administered intraperitoneally or orally

Cagrilintide is also studied in combination with semaglutide (the investigational pairing known as CagriSema ), where trials have reported substantial weight reductions beyond either agent alone [5] [6]

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