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As a typical mitochondrial - targeted peptide, SS-31 (elamipretide) can stabilize cardiolipin in the inner mitochondrial membrane, reduce electron leakage to inhibit ROS, inhibit the opening of mPTP to reduce the release of mtDNA and cell apoptosis, protect mitochondria and exert anti - inflammatory effects, and is effective on immune cells and parenchymal cells such as cardiomyocytes
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The fundamental distinction in subcutaneous vs intramuscular peptide injection lies in the tissue depth reached and the vascular density of that tissue
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10.3748/wjg.v22.i41.9127 28 DobricI.DrvisP.PetrovicI.ShejbalD.BrcicL.BlagaicA
Effect of targeted estrogen delivery using glucagon-like peptide-1 on insulin secretion, insulin sensitivity and glucose homeostasis
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