Published peer-reviewed studies include research on transected Achilles tendons in rats, quadriceps muscle crush injury models, surgically-induced and chemically-induced gastrointestinal lesions, NSAID-induced mucosal damage models, and ligament transection recovery studies
Most protocols dose by injection close to the site of injury (subcutaneous), though no human pharmacokinetic standard exists
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However, established damage not reversed, benefits limited to slowing progression and preventing further deterioration
Such studies have typically shown that pet owner adherence to veterinary recommendations for oral medications falls short of ideal coverage (5)