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Salcaprozate sodium, or SNAC, is one of the most advanced intestinal permeation enhancers that have been tested in clinical trials for oral delivery of macromolecules
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When looking at the percentage of participants that dropped out of the trial due to adverse effects, 2-6% of patients in the cagrilintide group discontinued treatment early while 7% of the participants receiving liraglutide discontinued treatment early, These findings were in comparison to only 3% of test subjects from the placebo group that discontinued treatment due to adverse events [1]
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