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Also, this review is supported by the project CICECOAveiro Institute of Materials, UID/50011/2025 (DOI 10.54499/UID/50011/2025) and LA/P/0006/2020 (DOI 10.54499/LA/P/0006/2020), financed by national funds through the FCT/MCTES (PIDDAC)
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can help reinforce realistic expectations about long-term treatment
Food & Drug Administration, 2019, 2023, 2024)
Product Attributes CAS # : 75921-69-6 Molecular Formula : C78H111N21O19 Sequence (AA) : Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 Molecular Weight : 1646.85 g/mol PubChem CID : 16132139 Half-Life : ~30-60 minutes (extended pigmentation effect lasts weeks) Synonyms : Afamelanotide, MT-I, MT-1, NDP-MSH, Scenesse, [Nle4, D-Phe7]-alpha-MSH Type : Synthetic research peptide (alpha-MSH analog, MC1R agonist) Research Focus : Skin Pigmentation & Photoprotection, Melanocortin Signaling Scientific References Afamelanotide for prevention of phototoxicity in patients with erythropoietic protoporphyria Human RCT | Regulatory Afamelanotide and narrowband UV-B phototherapy for the treatment of vitiligo Human RCT Photoprotection by melanocortin 1 receptor agonists Animal | In vitro Afamelanotide: a melanocortin analogue for photoprotection Observational | Animal The melanocortin-1 receptor: red hair and beyond In vitro | Observational Melanocortin 1 receptor signaling and skin pigmentation In vitro | Animal Scenesse (afamelanotide) European Medicines Agency assessment report Regulatory | Human RCT Included In The Box Every product arrives in a premium, custom-designed PEPTIDE.Power box , engineered for convenience, hygiene, and safe storage in your refrigerator
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