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Dysregulation of these pathways can lead to iron dyshomeostasis, resulting in the accumulation of labile iron in tissues and, ultimately, iron overloada condition increasingly recognized as a trigger for ferroptosis in various diseases, including PCOS

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HSL residue numbering differs across species and protein isoforms

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More importantly, the freezing and thawing process can affect the homogeneity of the solution

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GPX4 is also known as phospholipid hydroperoxide and exists as cytosolic, mitochondrial, and nuclear isoforms

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