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NAC group (rats were injected intraperitoneally with MTX on day 7 plus NAC 500 mg/kg/day throughout the experiment by oral gavage, plus Kolliphor EL from day 1- day 10) (Li et al., 2018
Low-dose oxidative stress triggers a conformational change in the Keap1 protein, releasing the transcription factor Nrf2
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Reinforce Roots
Time courses and bar graphs in this study are presented as mean values and standard errors of the mean across animals
Since cysteine is the rate-limiting factor in glutathione production, supplementing with NAC can significantly boost glutathione levels
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