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However, under conditions of iron overload, excess Fe 2+ in the LIP undergoes Fenton chemistry with H 2 O 2 , producing excessive ROS, promoting lipid peroxidation, and ultimately triggering ferroptosis (Zhao et al., 2025a)
Circulating vitamin C and digestive system cancers: Mendelian randomization study
The lysosome is an essential site for cellular iron storage and is indispensable for maintaining a stable iron level
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