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Semaglutide belongs to a class of medications known as GLP-1 receptor agonists, which mimic the effects of glucagon-like peptide-1 (GLP-1), a naturally occurring hormone produced in the intestines

Discontinuation in trials: retatrutide trial discontinuation due to adverse events was 6-10% across the higher-dose arms meaningful but lower than the dose-related side-effect profile would suggest, which indicates most participants tolerated the protocol

This leads to reduced food intake and significant weight loss in clinical trials and real-world use

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Over time, repeated clinic visits can easily mean thousands of dollars a month for those on a daily injection protocol

Medications prescribed only if clinically appropriate, based on completion of the required consultation