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Researchers following clinical data often apply the following dosing schedule to model metabolic health and weight loss outcomes: Weeks 14: 2 mg per week Weeks 58: 4 mg per week Weeks 912: 8 mg per week Weeks 1316: 12 mg per week (maintenance dose) This titration schedule helps minimize gastrointestinal side effects while maintaining consistent metabolic signaling

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Iron chelators, such as DFP, DFX, and DFO, have been shown to significantly reduce iron overload and serum iron levels in patients with thalassaemia [113,114,115]