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[176] An observational study on people with obesity and type 2 diabetes and heart failure with preserved ejection fraction, semaglutide had about a 42% lower risk of hospitalization for heart failure and all-cause death combined compared with sitagliptin

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Recent evidence indicates that protein misfolding and aggregation leading to ER stress is a major cause of neurodegeneration in ageing and in different neurodegenerative diseases such as Alzheimers disease (AD), Parkinsons disease (PD), Amyotrophic Lateral Sclerosis (ALS), and HD 22

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