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Most are probably linked to IGF-I over dosage
Protein was extracted from SH-SY5Y cells, N2A cells and mouse cortex using CellLytic buffer (Sigma) per manufacturer's instructions, separated by electrophoresis and blotted to PVDF membranes
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Crucially, HBV independently suppresses DNA repair capacity by downregulating poly(ADP-ribose) polymerase 1 (PARP1) via YTHDF2-mediated m6A methylationwithout enhancing ROS production or altering oxidative stress pathways [389, 391]
Chiang, P
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