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Annual price revisions under Japans NHI pricing system, which apply discounts to drugs with high-volume generic competition, have compressed the commercial tails of Japanese branded drug revenues significantly

Most patients regain approximately two-thirds of lost weight within one year of stopping GLP-1 therapy, based on the STEP 4 trial withdrawal data

Beneficial immune function also increased

What does success look like beyond weight

doi:10.1007/s10549-025-07678-7 Lus C, Dias J, Firmino-Machado J, et al

You've also said and I think this is something else we've learned over that time that obesity is not one thing