Iowa Orthopaedic J
As of 2026, the paper has not been formally retracted, but the Expression of Concern remains in force
These mechanisms are seen in controlled environments to understand: peptide-driven signaling, cellular stability, and biochemical regulation Properties of Epithalon (Peptide): Molecular Formula: C14H22N4O9 Molecular Weight: 390.35 g/mol CAS Number: 307297-40-1 PubChem CID: 219024 Synonyms: Epithalon, Epitalon, Epithalone, Ala-Glu-Asp-Gly Peptide Class: Synthetic tetrapeptide analog IUPAC Name: (4S)-4-[[(2S)-2-aminopropanoyl]amino]-5-[[(2S)-3-carboxy-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid Research Applications/Benefits of Epithalon (Peptide) Telomerase Activity Research Epithalon is great in laboratory studies to investigate telomerase-related mechanisms and chromosomal maintenance processes in experimental cell systems
56,57 Importantly, aberrant activation of oncogenic signaling pathways is another major driver of chemotherapy resistance
It was designed as a modified version of the C-terminal portion of human growth hormone (hGH)
Chang N, Li J, Lin S, Zhang J, Zeng W, Ma G, et al