AOD-9604 and 5-Amino-1MQ pass that test because beta-3 adrenergic activation and NNMT inhibition operate at entirely different nodes in fat metabolism
NAD+ metabolism and its roles in cellular processes during ageing
Science 306 , 13831386 (2004)
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Women can safely use AOD 9604 while taking birth control or hormone replacement therapy without interactions
Concerns about IGF-1 include potential effects on cancer risk, acromegalic changes with chronic elevation, and metabolic disruption