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However, GLP-1R internalization was previously found to be independent of -arrestin-1 14,34 , and a positive role for -arrestin-1 in stimulating insulin release has been reported 14

Diabetes, Obesity & Metabolism, 20 ,

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In a trial of Wegovy injection in adult patients with type 2 diabetes (T2D) and a BMI 27 kg/m 2 , hypoglycemia was reported in more patients treated with Wegovy versus placebo

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