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This dual action of stimulating insulin and inhibiting glucagon makes GLP-1 a powerful regulator of glucose metabolism
doi: 10.1016/S2213-8587(23)00356-X 13 JastreboffAMKaplanLMFrasJPWuQDuYGurbuzSet al
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Eli Lilly re-entered the spotlight in 2014 with Trulicity (dulaglutide) and again in 2022 with Mounjaro (tirzepatide)a dual agonist that activates both GLP-1 and GIP receptors, showing even greater weight loss results in trials
Neuropharmacology 101:98109
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