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Furthermore, it is helpful to evaluate whether the benefits of naltrexone-bupropion shown in the randomised controlled trial translate to the real-world clinical practice setting, since subjects followed up in the randomised controlled trial are often more intensively monitored and may be more motivated [13]

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Hormone Research in Paediatrics, 53(6), 274278

However, because of their low plasma and brain concentrations, it is unlikely that they contribute significantly to the anticonvulsant effects of VPA [10]