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Researchers can pharmacologically dissect these pathways using LY294002 (PI3K inhibitor) or U0126 (MEK inhibitor) to determine which downstream arm mediates a specific IGF-1 LR3 effect in their experimental system

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doi: 10.1016/j.ejim.2006.04.013 108 MaoucheNMeskineDAlamirBKoceirEA

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