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[9] It may often go unrecognized, as the body becomes used to feeling unwell

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For example, NAD+-dependent enzymes include the sirtuins (SIRT1-7), a family of protein deacetylases involved in gene expression, stress responses, and metabolic regulation, as well as poly(ADP-ribose) polymerases (PARPs) that assist in DNA repair

In combination, the blend is hypothesized to support faster and more comprehensive healing by acting on distinct phases of tissue repair 1-4

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