Every decision is made with your full physiology in view, not just your training log
There were no significant differences in respiratory rate between the groups at any time point, except for measurements at 50 min ( p = 0.025) and 120 min ( p = 0.012) after administration, where patients receiving Dex by any route had lower respiratory rates (Figure 3B)
Grauer GF, Greco DS, Getzy DM, et al
Top-Down Approach 2.4.2
This discrepancy between formal trial data and patient-reported experiences may reflect several factors: cold sensitivity might not have been specifically monitored in trials, it may be attributed to weight loss rather than the medication, or it might affect only a subset of patients
Patients might be women in their 30s with an autoimmune disease like lupus or people of any age exposed to such toxins as methamphetamines or, in the past, the fen-phen appetite suppressant drug of the 1990s, later withdrawn after being linked to heart disease