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Aged mice were divided into control and treatment groups, with the latter receiving intraperitoneal injections of FOXO4-DRI at doses of 0.5 mg/mL and 5 mg/kg every other day for 30 days, while controls received PBS

Possible signs include jawline prominence, enlarged hands/feet, coarse facial features, and organ enlargement (rare and associated with long-term abuse)

PMID: 34609538

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Knocking down ACTL6A had no impact on NRF2 expression (Supplementary Fig 6h)

We cook with it at home, restaurants cook with it when were out, its in our supermarket-bought salad dressings the list goes on