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We propose that adaptive resistance to cancer immunotherapy arises from the progressive dysfunction of tumor-specific T cells, which manifests as two interrelated yet distinct defects

The treatment itself takes only a few minutes, and most patients return immediately to normal daily activities, work, errands, or exercise afterward

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doi: 10.1016/j.diabres.2021.109119 4 ShahADLangenbergCRapsomanikiEDenaxasSPujades-RodriguezMGaleCPet al

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Study execution and results dissemination Pairwise effectiveness comparisons were executed across all databases using an open-source R package 56 developed using the OHDSI HADES tools